Jacksonville to Stuart is roughly 275 miles so my guess just straight riding it would take you probably 3 to 4 hours. Stuart would be a good place to stop for the night. Plenty of resturants and you have the beach. Here's a link to Stuart Fl that will help you. Lists all you need to know about Stuart, hotels, night life, scuba, etc. etc. etc.phil H said:How long will it take me to drive from Jacksonville to Stuart? I will probably stop for one night on the way down and Stuart looks like the logical place.