I also have limited miles on the P1 I mounted last fall just before an early snow put the Wing in hibernation (yet to be woke up). I used a 195/60-16 (not the run flat) and on the test rides can detect little difference from the E4 other than better straight line stability and less tar snake deviation. Leaning into a turn is ever so slightly more lean required to begin with then predicable and solid.A tire that you've mentioned (Pirelli P1 Cintura) is my first CT, I've mounted it sometimes last year and had a few thousand miles on it now. So, not as much of experience like others here but I do have my "first impressions".
I found that particular tire quite "flickable" and easy to ride. It is very close in weight to a MT and probably the closest in that MT "feel". Monk (Bob, someone with a wealth of Darkside experience) suggested that tire to me, based on the area where I live and the riding I do (mostly backroads, rolling hills, some mountains, very little highways). I was looking for handling, not mileage. And I believe I got that with Pirelli P1.
Now....a different tire might (and probably will) handle differently. Not better or worse, just different. And you might like one over the other based on your expectations. Heavier tire = more work in curves = more mileage...etc
This is not "defending" or "advocating" for Darkside, just merely an observation from a non-biased rider who happens to like that tire. Worth trying at least IMO.
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I'm no tire expert but so far I'm impressed and feel the increased traction in a all out emergency stop (especially in the wet) would be improved a lot. I'm often two up on the ABS equipped 2001 and occasionally towing the trailer.
The slightly larger profile of the 60 series over the popular 55 series also makes getting onto the centerstand easier.