Without being more specific on your routing from Denver to LA (via Vegas), I'm not sure I could suggest an alternate. You could ride north through California to Reno (multitude of ways to get there...), then cut east across US-50 to central Utah. Of course, you then have a multitude of paths to finish crossing the Rockies. SoCal to central Ohio is about 2200 miles, or 33 travel hours, accorting to Google - obviously, this is by interstates; it seems you're looking for an extra two or three days of travel, right?When coming to LA from Ohio I did US 36 to Denver then down thru Utah to Vegas, I'd like a different route back. Any suggestions? I can take 5 or 6 days if need be.
You also have the choice of a more southern route via southern Colorado, or northern Arizona & New Mexico; again, we could have you wandering the region for days.
A little more detail could be helpful.