I'd sure ride Skyline Drive off of 50 just west of Canon (Canyon) City.
According to MS Streets and Trips it's about an hour and a half round trip, unless you choke on Skyline Drive, then it might be longer...
Heading over to Westcliff would be a nice ride.
Maybe some of our friendly folks from down that way can give you some more pointers.
Have a good time while you're here!