Beware of deer, moose and other critters on the highway especially in the twilight hours. Other than that, the two legged kind are very friendly and you do not have to be concerned about safety. If you need help with anything (directions, mechanical troubles, tourist advice, whatever ..) just ask anybody - we'll be glad to help out. If you break down on the road, just wait a few minutes and someone will stop to help. Even the smaller towns will have community access centres that have free hi-speed computer terminals available for use by the public so if you need to check emails or this board for example you can gain access and it won't cost you anything, therefore you should not need to bring your own laptop. Similiarly most of the quality hotels also have a terminal for use by guests.
Have a great trip. If you get as far as eastern canada, look me up.